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<div id="gejawku" class="news_con"> <div id="yxcocid" class="jxbox clearfix"> <p style="text-indent: 2em; text-align: left;"><span style="background-color: rgb(249, 249, 249);">α腎上腺素受體阻斷藥?？妓幬铮悍油桌魉幚碜饔?/span><span style="background-color: rgb(249, 249, 249);">，相信是北京、上海、天津、重慶、湖南、浙江、福建、山東、河北、山西、安徽、江蘇、遼寧、江西、吉林、湖北、廣東、</span><span style="background-color: rgb(249, 249, 249);">廣西、寧夏、四川、河南、甘肅、陜西、西藏、海南、黑龍江、貴州、內蒙古、青海、云南、新疆、兵團公衛(wèi)執(zhí)業(yè)助理醫(yī)師考生關注的事情，醫(yī)學教育網小編整理內容如下：</span></p><p style="text-indent: 2em; text-align: left;"><strong>α腎上腺素受體阻斷藥-酚妥拉明</strong></p><p ptag="2793" plabel="5" style="text-indent: 2em; text-align: left;">【考頻指數】★★★</p><p ptag="2794" plabel="6" style="text-indent: 2em; text-align: left;">【考點精講】</p><p ptag="2795" plabel="7" style="text-indent: 2em; text-align: left;">1.酚妥拉明藥理作用</p><p ptag="2796" plabel="8" style="text-indent: 2em; text-align: left;">（1）阻斷α受體擴張血管，血壓下降。</p><p ptag="2797" plabel="9" style="text-indent: 2em; text-align: left;"><span plabel="10">（2）興奮心臟：阻斷突觸前膜α</span><sub ptag="2798" plabel="11">2</sub><span plabel="12">受體，使去甲腎上腺素釋放增多，激動心臟β</span><sub ptag="2799" plabel="13">1</sub><span plabel="14">受體的結果。</span></p><p ptag="2800" plabel="15" style="text-indent: 2em; text-align: left;">（3）其他作用：擬膽堿作用，興奮腸胃平滑??；組胺樣作用，使胃酸分泌增加，多與藥物不良反應有關。</p><p ptag="2801" plabel="16" style="text-indent: 2em; text-align: left;">2.臨床應用</p><p ptag="2802" plabel="17" style="text-indent: 2em; text-align: left;">（1）外周血管痙攣性疾?。喝缰藙用}痙攣的雷諾綜合征、血栓閉塞性脈管炎及凍傷后遺癥。</p><p ptag="2803" plabel="18" style="text-indent: 2em; text-align: left;">（2）去甲腎上腺素靜滴外漏處理。</p><p ptag="2804" plabel="19" style="text-indent: 2em; text-align: left;">（3）診治腎上腺嗜鉻細胞瘤。</p><p ptag="2805" plabel="20" style="text-indent: 2em; text-align: left;">（4）抗休克：感染性、心源性和神經源性休克。</p><p ptag="2806" plabel="21" style="text-indent: 2em; text-align: left;">（5）急性心肌梗死和頑固性充血性心力衰竭。</p><p ptag="2807" plabel="22" style="text-indent: 2em; text-align: left;">（6）藥物引起的高血壓。</p><p ptag="2808" plabel="23" style="text-indent: 2em; text-align: left;">【進階攻略】該類藥物種類較多，以酚妥拉明為代表。短效α受體阻斷藥冠心病、胃炎、潰瘍病者慎用。長效α受體阻斷藥腎功能不全及冠心病慎用。</p><p ptag="2809" plabel="24" style="text-indent: 2em; text-align: left;">【知識點隨手練】</p><p ptag="2810" plabel="25" style="text-indent: 2em; text-align: left;">一、A1型選擇題</p><p ptag="2811" plabel="26" style="text-indent: 2em; text-align: left;">1.外周血管痙攣性疾病可選用</p><p ptag="2812" plabel="27" style="text-indent: 2em; text-align: left;">A.山莨菪堿</p><p ptag="2813" plabel="28" style="text-indent: 2em; text-align: left;">B.異丙腎上腺素</p><p ptag="2814" plabel="29" style="text-indent: 2em; text-align: left;">C.酚妥拉明</p><p ptag="2815" plabel="30" style="text-indent: 2em; text-align: left;">D.普萘洛爾</p><p ptag="2816" plabel="31" style="text-indent: 2em; text-align: left;">E.間羥胺</p><p ptag="2817" plabel="32" style="text-indent: 2em; text-align: left;">2.能翻轉腎上腺素升壓作用的藥物是</p><p ptag="2818" plabel="33" style="text-indent: 2em; text-align: left;">A.M受體阻斷藥</p><p ptag="2819" plabel="34" style="text-indent: 2em; text-align: left;">B.N受體阻斷藥</p><p ptag="2820" plabel="35" style="text-indent: 2em; text-align: left;">C.β受體阻斷藥</p><p ptag="2821" plabel="36" style="text-indent: 2em; text-align: left;">D.α受體阻斷藥</p><p ptag="2822" plabel="37" style="text-indent: 2em; text-align: left;"><span plabel="38">E.H</span><sub ptag="2823" plabel="39">1</sub><span plabel="40">受體阻斷藥</span></p><p ptag="2824" plabel="41" style="text-indent: 2em; text-align: left;">【知識點隨手練參考答案及解析】</p><p ptag="2825" plabel="42" style="text-indent: 2em; text-align: left;">一、A1型選擇題</p><p ptag="2826" plabel="43" style="text-indent: 2em; text-align: left;">1.【答案及解析】C。酚妥拉明為α腎上腺素受體阻滯藥，用于外周血管痙攣性疾病，如肢端動脈痙攣性疾病及血栓閉塞性脈管炎。</p><p ptag="2827" plabel="44" style="text-indent: 2em; text-align: left;">2.【答案及解析】D。α腎上腺素受體阻斷藥可拮抗腎上腺素的α型作用，使激動藥的量效曲線平行右移，可使腎上腺素的升壓作用翻轉為降壓作用，這種現象稱為“腎上腺素作用的翻轉”。</p><p style="text-indent: 2em; text-align: left;"><strong>溫馨提示</strong>：2021年<a href="http://thedailypurge.net/gongweizhuliyishi/" target="_blank" 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